MOLVAL FORT®, a unique formula
Liposolubilized monacolin K
Monacolin K is naturally present in red yeast rice. The Molval® Fort formula features the solubilization of monacolin K in omega-3-rich fish oil (EPA/DHA).
This innovative process, developed by Laboratoire Dielen, facilitates monacolin K absorption. Liposolubilized monacolin K can then be absorbed via the lipid absorption pathway.
The nutritional complex
Molval® Fort combines certain nutrients such as omega-3 which contribute to normal heart function.
The formula contains coenzyme Q10 or Ubiquinone. It is also liposolubilized in fish oil.
EPA and DHA omega-3 fish oils are selected for their nutritional qualities.
A formula based on science
The components of the Molval® Fort formula have historically been studied.
Docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) help maintain normal blood triglyceride levels. The beneficial effect is obtained by consuming 2 g of EPA and DHA per day.
EPA and DHA contribute to normal heart function. The beneficial effect is obtained by consuming 250 mg of EPA and DHA daily.
The Molval® Fort formula has benefited from a clinical study carried out in doctors' surgeries in France.
Health claim
*EPA and DHA help maintain normal blood triglyceride levels. The beneficial effect is achieved with a daily intake of 2 g of EPA and DHA. Consumption should not exceed 5 g per day of EPA and DHA combined.
Clinical trial references for Molval® Fort
1. Cicero, A.F.G.; Derosa, G.; Parini, A.; Maffioli, P.; D'Addato, S.; Reggi, A.; Giovannini, M.; Borghi, C. Red Yeast Rice Improves Lipid Pattern, High-Sensitivity C-Reactive Protein, and Vascular Remodeling Parameters in Moderately Hypercholesterolemic Italian Subjects. Nutrition Research 2013, 33, 622-628, doi:10.1016/j.nutres.2013.05.015.
2. Cicero, A.; Morbini, M.; Parini, A.; Urso, R.; Rosticci, M.; Grandi, E.; Borghi, C. Effect of Red Yeast Rice Combined with Antioxidants on Lipid Pattern, Hs-CRP Level, and Endothelial Function in Moderately Hypercholesterolemic Subjects. TCRM 2016, 281, doi:10.2147/TCRM.S91817.
3. Heber, D.; Yip, I.; Ashley, J.M.; Elashoff, D.A.; Elashoff, R.M.; Go, V.L.W. Cholesterol-Lowering Effects of a Proprietary Chinese Red-Yeast-Rice Dietary Supplement. The American Journal of Clinical Nutrition 1999, 69, 231-236, doi:10.1093/ajcn/69.2.231.
4. Li, Y.; Jiang, L.; Jia, Z.; Xin, W.; Yang, S.; Yang, Q.; Wang, L. A Meta-Analysis of Red Yeast Rice: An Effective and Relatively Safe Alternative Approach for Dyslipidemia. PLoS ONE 2014, 9, e98611, doi:10.1371/journal.pone.0098611.
5. Moriarty, P.M.; Roth, E.M.; Karns, A.; Ye, P.; Zhao, S.-P.; Liao, Y.; Capuzzi, D.M.; Bays, H.E.; Zhang, F.; Liu, S.; et al. Effects of Xuezhikang in Patients with Dyslipidemia: A Multicenter, Randomized, Placebo-Controlled Study. Journal of Clinical Lipidology 2014, 8, 568-575, doi:10.1016/j.jacl.2014.09.002.
6. Verhoeven, V.; Lopez Hartmann, M.; Remmen, R.; Wens, J.; Apers, S.; Van Royen, P. Red Yeast Rice Lowers Cholesterol in Physicians - a Double Blind, Placebo Controlled Randomized Trial. BMC Complement Altern Med 2013, 13, 178, doi:10.1186/1472-6882-13-178.
Health benefits :
The benefits of monacolin K
Derived from a microscopic fungus(monascus purpureus), monacolin K is traditionally used in Chinese medicine.
Numerous scientific studies have demonstrated the effects of monacolin K from red yeast rice. A dose of less than 3 mg/day is now authorized in food supplements.
Omega-3 and cardiovascular health
Theeffect of omega-3 on heart health is well established scientifically. These properties are explained by their action on blood triglycerides, blood pressure and heart function.
The properties of coenzyme Q10
Similar in chemical structure to vitamin K, coenzyme Q10 (CoQ10) is produced naturally by the body. It is present in almost all cells. It is involved in the cellular Krebs cycle.
Directions for use
How many capsules?
One capsule a day, to be swallowed with a glass of water.
When should you take it?
We recommend taking your capsule in the evening, with food.
How long does a box last?
At 1 capsule a day, each box of 30 capsules contains 1 month's supplementation.
At 1 capsule a day, each box of 90 capsules contains 3 months of supplementation.
For how long?
1-month renewable supplementation.
If you experience any side effects, ask your pharmacist for advice or consult a doctor and contact the Dielen laboratory's consultant pharmacist.
Precautions for use
- MOLVAL® FORT is not a medicine. It is not a substitute for a balanced and varied diet.
- It should not be consumed by pregnant or breast-feeding women, by people under 18, or by people over 70.
- Under medical supervision in people with pathologies such as renal failure, muscular pathology or untreated hypothyroidism, or suffering from liver damage with high transaminase levels.
- Should not be consumed if you are taking cholesterol-lowering medication.
- Do not consume if
you are already taking other products containing red yeast rice. - Not recommended for heavy consumers of grapefruit (juice or fruit) or alcohol, or for people allergic to fish.
- Do not exceed the recommended dose.
- Keep out of reach of children.
- If you have any health problems, ask your doctor for advice before using this product.
Composition
| For 1 capsule | %VNR* | |
|---|---|---|
| Monacolin K Red yeast rice | 2,9 mg | - |
| Omega-3 Of which EPA Of which DHA | 167 mg 95 mg 62 mg | 38% 25% |
| Coenzyme Q10 | 16,7 mg | - |
- EPA-DHA omega-3 fish oil
- Red rice yeast with 1.5% monacolin K
- Fish gelatin (shell)
- Firming agent: vegetable glycerin
- Thickener: glycerol monostearate
- Coenzyme Q10: Ubiquinone
- Emulsifier: rapeseed lecithin
- Antioxidants: natural tocopherol extract, rosemary extract
Science: Scientific proof of Laboratoire Dielen
Red yeast rice is a microscopic fungus grown on rice. This micro-organism produces a characteristic red pigment that gives the yeast its name. Dried and reduced to powder, yeast is used as a colorant in a variety of food preparations.
Red yeast rice contains monacolins, including monacolin K.
European regulations limit the dose of monacolin k in food supplements to less than 3 mg per day for an adult. This supplementation is accompanied by the above-mentioned recommendations for use.
The body naturally produces CoQ10 according to its needs. It is therefore not considered an essential nutrient. No recommended daily intake has been determined.
However, some studies have shown that with age, the body produces less and less Co Q10.
Cardiovascular disease is the second leading cause of death in France. Since the major observational studies, we know that a diet rich in omega-3 (fish and seafood) contributes to cardiovascular protection.
Other scientific data have also shown that consumption of omega-3 fatty acids contributes to :
- Maintenance of normal blood pressure at a dose of 250 mg EPA and DHA per day
- A reduction in blood triglycerides at a dose of 2 g/day.
From Omega-3 garas (EPA), the body produces important mediators that regulate important biological and physiological functions in our health. Leukotrienes, prostaglandins, prostacyclins and thromboxanes regulate inflammatory response, platelet aggregation and coagulation, and vasodilation, respectively.
On the other hand, other mediators obtained from omega-6 fatty acids (arachidonic acid) have antagonistic effects. That's why it's important to have a good balance between omega-6 and omega-3 intake.
Omega-3 EPA and DHA from fish oil help :
- normal heart function. The beneficial effect is obtained by consuming 250 mg of EPA and DHA per day.
- maintaining normal blood pressure at a dose of 2 g EPA and DHA per day
- maintaining normal triglyceride levels in the blood. The beneficial effect is obtained by daily consumption of 2 g of EPA and DHA.
1. Cicero, A.F.G.; Derosa, G.; Parini, A.; Maffioli, P.; D'Addato, S.; Reggi, A.; Giovannini, M.; Borghi, C. Red Yeast Rice Improves Lipid Pattern, High-Sensitivity C-Reactive Protein, and Vascular Remodeling Parameters in Moderately Hypercholesterolemic Italian Subjects. Nutrition Research 2013, 33, 622-628, doi:10.1016/j.nutres.2013.05.015.
2. Cicero, A.; Morbini, M.; Parini, A.; Urso, R.; Rosticci, M.; Grandi, E.; Borghi, C. Effect of Red Yeast Rice Combined with Antioxidants on Lipid Pattern, Hs-CRP Level, and Endothelial Function in Moderately Hypercholesterolemic Subjects. TCRM 2016, 281, doi:10.2147/TCRM.S91817.
3. Heber, D.; Yip, I.; Ashley, J.M.; Elashoff, D.A.; Elashoff, R.M.; Go, V.L.W. Cholesterol-Lowering Effects of a Proprietary Chinese Red-Yeast-Rice Dietary Supplement. The American Journal of Clinical Nutrition 1999, 69, 231-236, doi:10.1093/ajcn/69.2.231.
4. Li, Y.; Jiang, L.; Jia, Z.; Xin, W.; Yang, S.; Yang, Q.; Wang, L. A Meta-Analysis of Red Yeast Rice: An Effective and Relatively Safe Alternative Approach for Dyslipidemia. PLoS ONE 2014, 9, e98611, doi:10.1371/journal.pone.0098611.
5. Moriarty, P.M.; Roth, E.M.; Karns, A.; Ye, P.; Zhao, S.-P.; Liao, Y.; Capuzzi, D.M.; Bays, H.E.; Zhang, F.; Liu, S.; et al. Effects of Xuezhikang in Patients with Dyslipidemia: A Multicenter, Randomized, Placebo-Controlled Study. Journal of Clinical Lipidology 2014, 8, 568-575, doi:10.1016/j.jacl.2014.09.002.
6. Verhoeven, V.; Lopez Hartmann, M.; Remmen, R.; Wens, J.; Apers, S.; Van Royen, P. Red Yeast Rice Lowers Cholesterol in Physicians - a Double Blind, Placebo Controlled Randomized Trial. BMC Complement Altern Med 2013, 13, 178, doi:10.1186/1472-6882-13-178.
Frequently asked questions
Molval® Fort should not be taken as an adjunct to statin-type cholesterol treatment.
Molval® Fort can be taken continuously, but it is important to be alert to any side effects that may be associated with long-term supplementation.
In this case, it's important to ask your pharmacist for advice, or consult your GP to arrange regular follow-up care.
As part of its ISO 22000 certification, the Dielen laboratory has set up a follow-up service for all information and complaints. A pharmacist advisor is available on the website messaging service and by telephone on 02 33 23 43 90.
It's important to ensure that monacolin K is well-tolerated, as it can weaken muscles, liver and kidneys. After the age of 70, muscles, liver and kidneys are often more fragile.
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