DIELEN® GROSSESSE, a unique formula
A formula based on science
The Dielen® Grossesse formula is based on a review of current scientific literature carried out in collaboration with the CERMN laboratory at the University of Caen in Normandy. This study was published in the international scientific journal " Nutrients" [2]. It defined the nature and dosage of each nutrient on the basis of up-to-date scientific data.
The 5S of an original formula
- Safety: the components of the Dielen® Grossesse formula are selected for their quality and dosed according to current scientific recommendations for the nutritional needs of pregnant and breastfeeding women and their babies. This nutritional complex is formulated, sourced and dosed to guarantee total safety for mother and baby. Dielen® Grossesse is a dietary supplement with no artificial flavoring, coloring or GMOs.
- Simplicity : a single formula from the desire to conceive to the end of breastfeeding.
- Synergy : The formula is designed to meet the nutritional needs of both the mother and the embryo, then the fetus, and finally the breast-fed infant.
- Sourcing : Dielen® Pregnancy combines quality nutrients selected for :
- Nutritional benefits
- Their bioavailability
- Their tolerances
- Their stabilities
- Their sustainable production
- Separation of doses: the choice of a separate dose, with one capsule in the morning and one in the evening, guarantees nutrient stability and efficacy. Separation of iron and omega-3 to avoid oxidation of the omegas. Separation of vitamins and minerals to prevent vitamin degradation.
Dielen gastro-protective film coating
Dielen® Grossesse supplementation consists of one capsule and one capsule taken daily. Both benefit from the Dielen film coating, which protects the nutrients from gastric acidity by delaying their release into the intestine. Dielen film-coating uses no chemical additives, only gums of natural origin.
Health benefits :
DHA, an essential omega-3 during pregnancy
DHA contributes to the health of both the pregnant woman and the baby:
- For mothers, a good DHA omega-3 status has positive effects on their psychological and emotional well-being.
- In babies, DHA contributes to the normal development of the brain, nervous system and vision.
After delivery, DHA still plays an important role as the baby's nervous system continues to develop. During breastfeeding, DHA is essential for the functioning of the baby's nervous system.
The role of vitamins B6 and B9
Vitamin B6 helps metabolize proteins and carbohydrates. It is also involved in the formation of red blood cells and the development of the nervous and immune systems.
Vitamin B9 plays a role in the growth of maternal tissues. It also contributes to the development of the nervous system and red blood cells.
Vitamin D3, a must-have
During pregnancy, vitamin D3 contributes to the absorption of calcium and phosphorus, essential elements for bone mineralization in both mother and fetus. In this way, it ensures the formation of the baby's bones and teeth. It contributes to the health of muscles, nerves and the immune system.
The role of magnesium
Magnesium isone of the essential minerals for both mother and fetus. The recommended daily intake for an adult woman is 360 mg of magnesium. But during pregnancy, this requirement increases. to provide the fetus with what it needs for the development of bone tissue.
Iron, the trace element to follow
Iron contributes to the normal formation of red blood cells in both mother and fetus, which carry oxygen in the blood.
During pregnancy, iron requirements increase significantly.
The key role of iodine from conception to breastfeeding
During pregnancy, iodine requirements increase.
Iodine contributes to normal thyroid hormone production and normal thyroid function in both mother and baby
Directions for use
For whom, for what?
- Women of childbearing age
- The parental project and the desire to become pregnant
- Pregnant or breast-feeding women
What dose?
One capsule AND one capsule a day, to be swallowed with a glass of water.
When should you take it?
Take one capsule in the morning and one in the evening.
For how long?
Dielen® Pregnancy supplementation is recommended from the desire to conceive until the end of breastfeeding.
How long does a box last?
One capsule and one capsule per day, each box contains 1 month of supplementation.
Precautions for use
- Not recommended for those allergic to fish.
- Do not exceed the recommended daily dose.
- Not a substitute for a varied, balanced diet and a healthy lifestyle.
- Not recommended for thyroid disorders
- Ask your pharmacist for advice before taking any supplements.
- Store away from moisture and heat.
- Keep out of reach of young children.
Composition
| For 1 capsule | %VNR* | |
|---|---|---|
| Omega-3 DHA | 250 mg | - |
| Vitamin B9 including : MTHF QUATREFOLIC® Folic Acid | 400 µg 200 µg 200 µg | 200% |
| Vitamin B6 | 350 µg | 25% |
| Vitamin D3 | 10 µg | 200% |
| For 1 capsule | %VNR* | |
|---|---|---|
| Iron - Bisglycinate | 14 mg | 100% |
| Proteochelated magnesium | 100 mg | 27% |
| Iodine Potassium iodide | 100 µg | 67% |
For one capsule :
- Fish oils with omega-3 DHA (antioxidants: tocopherols, rosemary extract)
- Fish gelatin (shell)
- Vitamin B6 (pyridoxine hydrochloride)
- Vitamin B9 (methyltetrahydrofolate as glucosamine salt)
- Vitamin B9 (folic acid)
- Vitamin D3 (cholecalciferol)
- Firming agent: vegetable glycerin
- Thickener: mono and diglycerides of fatty acids
- Glazing agent: shellac
- Glazing agent: gum arabic
- May contain traces of shellfish
For one capsule :
- Proteochelated marine magnesium: magnesium oxide and rice protein hydrolysate
- Fish gelatin (shell)
- Iron bisglycinate
- Anticaking agent: rice starch
- Glazing agents: shellac and gum arabic
- Glazing agent: vegetable glycerin
- Potassium iodide (iodine)
Science:
One in three women suffers from a vitamin and trace element deficiency during pregnancy. During this period, iron and vitamin D requirements double, and iodine and vitamin B9 needs increase by 30%.
The French health agency ANSES [2] has published an opinion updating the dietary guidelines of the French National Nutrition and Health Program (PNNS) for pregnant and breastfeeding women, highlighting their inadequate micronutrient intake:
- Between 25% and 50% have inadequate magnesium intakes,
- 45% have inadequate iron intakes,
- Between 50 and 75% have inadequate intakes of DHA and vitamin B6
Figure 1: Risks of nutrient deficiencies in the population of pregnant women in France (Avis ANSES 2017, Etude ELFE).
The study carried out by Laboratoire Dielen in collaboration with Pôle Santé and the Faculty of Pharmacy at the University of Caen Normandie and published, in 2021, in the scientific journal Nutrients[3] aimed to address two main issues:
- Is there any evidence that the dietary intake of pregnant and breastfeeding women is not in line with recommendations?
- Should pregnant and breast-feeding women take supplements?
These issues highlighted :
- The link between the prenatal environment and the onset of pathologies in adulthood,
- Updated PNNS dietary guidelines for pregnant and breast-feeding women
- The impact of early exposure of the child to environmental nutritional factors through food during the so-called "1000-day period": the period from conception to the child's 2nd birthday.
This study was based on scientific literature data from 85 articles concerning pregnant and breastfeeding women in the USA, Canada and Europe.
The results of this study highlighted the following conclusions:
- Inadequate food intake by pregnant and breastfeeding women.
- Nutrition-related health risks are specific to each of the populations studied. They can be limited by a varied, healthy diet,
- The results of clinical studies are favorable to supplementation for nutrients whose needs are not easily covered by a healthy and varied diet, or due to specific diets.
The data collected at the end of the study will enable us to analyze the relationship between maternal nutrition, fetal growth and child development.
As early as the third week of pregnancy, the fetal nervous system begins to take shape. Then the brain develops rapidly: several tens of billions of neuronal cells are produced in just a few months.
DHA, also known as "cervonic acid", makes up the membranes of the brain's neurons. It is essential for normal brain function.
Thereafter, during the last trimester of pregnancy, the baby's brain continues to grow, increasing in volume by 3 to 5 times.
At birth, the baby's brain is 60% lipid and weighs almost 300g. It will continue to develop rapidly during the first two years of life.
To meet the baby's needs right from the start of pregnancy, we recommend increasing your intake of omega-3 essential fatty acids as soon as you become pregnant.
If, during pregnancy, the body's iron requirements are not met, it draws on its reserves, located mainly in the liver. Insufficient dietary iron intake can lead to fatigue.
Vitamin B9 (folic acid) is important from the very first days of pregnancy, as it is involved in cell division.
As early as the4th week of pregnancy, maternal nutritional deficiency can cause serious malformations of the embryo's nervous system, as well as in utero growth retardation.
A lack of folic acid (vitamin B9) is diagnosed by a simple blood test. However, 1 in 2 women has a folate intake of less than 2/3 of the recommended dietary allowance. And over 50% of women do not metabolize folic acid correctly.
The French National Nutrition and Health Program (PNNS) recommends systematic supplementation as soon as you become pregnant.
Vitamin B9 contributes to the growth of maternal tissue during pregnancy.
Omega-3 DHA contributes to the normal development of the eyes (retina) and brain of the foetus and breast-fed child. The beneficial effect is obtained by consuming 200 mg of DHA daily, in addition to the daily intake of omega-3 fatty acids recommended for adults, i.e. 250 mg of DHA and EPA.
[1] Avis de l'ANSES Saisine n°2017-SA-0141 du 23 décembre 2019 relatif à l'actualisation des repères alimentaires du PNNS pour les femmes enceintes ou allaitantes - Kadawathagedara M, et al. Adéquation des consommations alimentaires des femmes enceintes de l'étude ELFE aux recommandations du Programme National Nutrition Santé. Cahiers de nutrition et de diététique (2017).
[2] Nutrient Requirement during Pregnancy anc Lactation - Nutrients 2021, 13, 6992.
Frequently asked questions
It is recommended to start supplementation as soon as pregnancy is desired, and to continue until the end of breast-feeding.
Taking food supplements during pregnancy, as part of a healthy, varied diet and healthy lifestyle, provides specific, well-dosed nutrients.
Supplements must be taken daily over the long term.
Today, certain dietary habits do not provide the vitamins and minerals needed by mother and fetus.
Dielen® Grossesse is a formula developed from up-to-date scientific literature and validated by a published research program.
This study selected the nutrients in the complex to meet the specific needs of women from conception to breastfeeding. Dosages are adapted to women who are pregnant or who wish to become pregnant, and those who are breast-feeding.
Laboratoire Dielen has selected forms of vitamins and minerals which scientific studies have shown to be optimally assimilated, to promote the efficacy and tolerance of supplementation.
The definition of NRVs is given by the FAO/WHO Codex Alimentarius in its "Guidelines for nutrition labelling": "It is a set of numerical values based on scientific data and used for the purposes of nutrition labelling and relevant claims".
These values have been assessed by independent nutrition experts to establish reference intakes for the general population.
For certain applications or specific populations, the NRVs can be exceeded. In the case of Dielen® Grossesse, certain vitamins and minerals are at 200% of the NRVs, as they are essential for pregnant women and their babies. Nutritional deficiencies in pregnant women are frequent.
Magnesium and vitamin B6 are supplied as co-factors of vitamin D. For this reason, they do not meet 100% of the NRVs.
With regard to iodine, an opinion issued by the French health agency ANSES has highlighted the risk of overdosing with an intake of between 120 and 150 µg, hence the choice of 100 µg.
Folic acid is the precursor of 5 Methyl Tetrahydrofolate (MTHF), the "active" form of vitamin B9.
The Dielen formula combines the 2 forms in accordance with the MTHF QUATREFOLIC® patent to guarantee stability.
Scientific publications show that some women have difficulty converting folic acid into its vitamin-active form (MTHF). Certain genotypes (notably TT) may be more deficient in vitamin B9.
Iron bisglycinate is well suited to supplementation. Its combination with an amino acid (glycine) enhances intestinal absorption. It's a balance between nutritional intake and digestive comfort.
Also known as potassium salt, potassium iodide has the advantage of being well assimilated by the body.
Protein-chelated magnesium is a blend of marine magnesium and rice peptides. This process forms a complex between the peptides and the magnesium. This complex, known as a chelate, is absorbed via the amino acid pathway. According to bioavailability studies, this form is well assimilated.
Dielen® Grossessse contains only one neutral, certified organic vegetable additive: rice starch.
Observational studies show that vitamin B12 deficiency is limited in the general population of France. It exists mainly in vegans, as vitamin B12 is present in foods of animal origin.
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